Biological and Genetic Biobanks Registry for Primary Immunodeficient, Asthmatic and Allergic patients
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Background
Biobank is a collection of resources containing biological and genetic materials that help store valuable samples. Establishing a biobank makes easy to access samples for assessing their characteristics. Our biobank consists of four separate biobanks including DNA, HLA, serum and cell banks. Our aim is to standardize banking the samples of patients and their families who referred to Immunology, Asthma and Allergy Research Institute (IAARI) and suffered from primary immunodeficiency (PID), asthma and allergy.
 
Aims
IAARI's biobank was established in 2006 with DNA and serum banks, then cell and HLA banks were added in 2012. All of the cases with diagnosis of PID, asthma and allergy entered in this registry and after taking informed consent, their samples were stored in the biobank.  
 
  • Establishing a biobank makes easy to access samples for assessing their characteristics.
  •  Our biobank consists of four separate biobanks including DNA, HLA, serum and cell banks.
  • Our aim is to standardize banking the samples of patients and their families who referred to Immunology, Asthma and Allergy Research Institute (IAARI) and suffered from primary immunodeficiency (PID), asthma and allergy.
  • IAARI's biobank was established in 2006 with DNA and serum banks, then cell and HLA banks were added in 2012.
  • All of the cases with diagnosis of PID, asthma and allergy entered in this registry and after taking informed consent, their samples were stored in the biobank. 
  • This biobank can be used to early diagnosis of PID genetics, and finding matched hematopoietic stem cell transplantation (HSCT) candidates for them.
  •  Also it can be helpful for investigating prospective genetic and familial surveys.
  •  This also decreases need for cost and re-sampling from patients.
 
 
Activities
This biobank can be used to early diagnosis of PID genetics, and finding matched hematopoietic stem cell transplantation (HSCT) candidates for them. Also it can be helpful for investigating prospective genetic and familial surveys. This also decreases need for cost and resampling from patients.
Up to now, we stored a total of 3288 DNA samples from PID patients and their relatives, 450 serums from allergic patients, 186 samples of asthmatic patients, more than 700 HLA samples of healthy donors' volunteers, and 43 cell samples from PID patients.
 
 
2016/2/15


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